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首页> 外文期刊>Histopathology: Official Journal of the British Division of the International Academy of Pathology >Ectopic hamartomatous thymoma is distinct from lipomatous pleomorphic adenoma in lacking PLAG1 aberration
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Ectopic hamartomatous thymoma is distinct from lipomatous pleomorphic adenoma in lacking PLAG1 aberration

机译:异位错构瘤性胸腺瘤与脂肪性多形性腺瘤的区别在于缺乏PLAG1畸变

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摘要

Ectopic hamartomatous thymoma (EHT) or branchial anlage mixed tumour is a rare benign tumour of the lower neck showing an admixture of spindle cells, epithelial islands, and adipose cells. The exact tumour derivation is uncertain, but an origin from the branchial arch, a remnant of primitive ectoderm from the cervical sinus of His, is postulated. The differential diagnoses of EHT include benign and malignant tumours with a biphasic pattern. One entity with a close morphological similarity is lipomatous pleomorphic adenoma or pleomorphic adenoma with lipomatous differentiation.
机译:异位错构瘤性胸腺瘤(EHT)或分支性肛门混合瘤是下颈部罕见的良性肿瘤,表现为梭形细胞,上皮岛和脂肪细胞的混合体。确切的肿瘤来源尚不确定,但推测其起源于小His弓,即His颈窦原始外胚层的残留。 EHT的鉴别诊断包括具有双相型的良性和恶性肿瘤。具有紧密的形态相似性的一个实体是脂瘤性多形性腺瘤或具有脂瘤性分化的多形性腺瘤。

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