Radiation-Induced Crosslinking of Thymine with Cysteamine: Cysteamine Attachment to the Methyl Group of Thymine

摘要

5-S-Cysteaminemethyluracil (the product of cysteamine attachment to the methyl group of thymine) was isolated from irradiated solutions containing thymine and cysteamine and identified. This compound was formed in the reaction of thiyl radicals with 5-methyleneuracil-5-yl radicals formed by H-atom abstraction from the methyl group of thymine. This product was not formed in the presence of oxygen.