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Can homemade fit testing solutions be as effective as commercial products?

机译:自制的身体适应性测试解决方案能否与商业产品一样有效?

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Abstract. Background: Fit testing is used to determine whether a N95 mask will provide respiratory protection for the wearer by preventing inhalation of airborne transmitted microorganisms. National guidelines recommend that healthcare workers (HCW) who use N95 masks require fit testing. Quantitative fit testing requires the purchasing and use of fit testing solutions and associated equipment. In high volume, these solutions are expensive and may not be readily available, as was seen in the 2009 H1N1 influenza pandemic. The aim of this study was to determine how a homemade solution compared against a commercially available product and a placebo.Methods: A fit test was performed on the same person, on three separate occasions, using three different solutions -commercial (45% sodium saccharin), homemade (to be disclosed) and placebo (water). The solution was double blinded and solutions were chosen and administered in a random order.A total of 48 people participated in this study. At the threshold testing stage, 8.3%didnottaste any solution, 16.7% of people could taste the placebo, 89.6% could taste the commercial solution and 91.7% could taste the homemade solution. All persons who could taste the commercial solution could taste homemade solution.Conclusion: The findings of our study suggest that fit testing solutions could be made locally with a similar effect to that of commercial products, that quantitative fit testing is unreliable and that serious consideration should be given to the role of quantitative fit testing in future guidelines and standards. We recommend that this study be conducted on a larger scale to support our findings.
机译:抽象。背景:适合性测试用于确定N95面罩是否通过防止吸入空气传播的微生物来为佩戴者提供呼吸保护。国家指南建议使用N95口罩的医护人员(HCW)需要进行适合性测试。定量拟合测试需要购买和使用拟合测试解决方案和相关设备。如2009年H1N1流感大流行中所见,这些解决方案的价格昂贵,而且价格昂贵,可能无法立即获得。这项研究的目的是确定自制溶液与市售产品和安慰剂的比较。方法:在三种不同情况下,使用三种不同的溶液在同一个人上进行同一性测试-商业(45%糖精钠) ),自制(待公开)和安慰剂(水)。解决方案是双盲的,选择解决方案并按随机顺序进行管理。共有48人参加了本研究。在阈值测试阶段,有8.3%Didnottaste可以溶解任何溶液,16.7%的人可以品尝到安慰剂,89.6%的人可以品尝到商业溶液,91.7%的人可以品尝到自制溶液。结论:我们的研究结果表明,可以在本地制造拟合测试溶液,其效果与商业产品相似,定量拟合测试不可靠,应认真考虑在未来的指南和标准中承担定量适合性测试的作用。我们建议更大规模地进行这项研究,以支持我们的发现。

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