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Characteristics and survival rate of elderly patients with colorectal cancer detected by immunochemical occult blood screening.

机译:免疫化学潜血筛查法检测老年大肠癌的特征和生存率。

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BACKGROUND/AIMS: A comparative study was carried out to clarify the clinicopathological features and survival rate of elderly patients with colorectal cancer diagnosed by immunochemical fecal occult blood screening. METHODOLOGY: The study subjects included 208 patients with colorectal cancer, who were divided into 2 groups based on their ages: 52 patients aged 75 years and over (older group) and 156 patients aged 50-74 years (younger group). The 2 groups were compared in terms of their individual factors, including site, size, Dukes' classification, histo-pathological type of their cancer lesions and 5-year survival rate. RESULTS: There was a significant difference in prevalence of tumor sites between the older and younger groups (P < 0.05). Particularly, the frequency of right colon cancers was higher in the older group (34.6%) than in the younger group (20.5%), but there were no differences found in any other factors such as size, Dukes' classification, and histopathological type. Survival rate was almost the same between the 2 groups. CONCLUSIONS: These results suggest that elderly patients are susceptible to right colon cancer but there is no difference in the clinicopathological characteristics and 5-year survival rate between older and younger patients with colorectal cancer detected by immunochemical fecal occult blood test. The older as well as younger people should be encouraged to attend the screening program for colorectal cancer by immunochemical fecal occult blood test.
机译:背景/目的:进行了一项比较研究,以阐明通过免疫化学粪便潜血筛查诊断出的老年结直肠癌患者的临床病理特征和生存率。方法:研究对象包括208例结直肠癌患者,根据年龄将其分为两组:年龄在75岁及以上的52例患者(老年组)和年龄在50-74岁的156例患者(年轻组)。比较两组的个体因素,包括部位,大小,Dukes分类,癌病变的组织病理学类型和5年生存率。结果:老年组和年轻组的肿瘤部位患病率存在​​显着差异(P <0.05)。特别是,老年组(34.6%)的右结肠癌发生率高于年轻组(20.5%),但在其他任何因素如大小,杜克分类和组织病理学类型方面均无差异。两组的存活率几乎相同。结论:这些结果表明,老年患者对右结肠癌敏感,但通过免疫化学粪便潜血试验检测的老年和年轻结直肠癌患者的临床病理特征和5年生存率没有差异。应鼓励老年人和年轻人参加大肠癌的筛查计划,方法是进行粪便隐血免疫化学检测。

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