XRCC1 rs25487 genetic variant and TP53 mutation at codon 249 predict clinical outcomes of hepatitis B virus-related hepatocellular carcinoma after hepatectomy: A cohort study for 10 years' follow up

Yu Long; Liu Xiaoguang; Han Chuangye; Lu Sichong; Zhu Guangzhi; Su Hao; Qi Wei; Liao Xiwen; Peng Tao

首页> 外文期刊>Hepatology research: the official journal of the Japan Society of Hepatology >XRCC1 rs25487 genetic variant and TP53 mutation at codon 249 predict clinical outcomes of hepatitis B virus-related hepatocellular carcinoma after hepatectomy: A cohort study for 10 years' follow up

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XRCC1 rs25487 genetic variant and TP53 mutation at codon 249 predict clinical outcomes of hepatitis B virus-related hepatocellular carcinoma after hepatectomy: A cohort study for 10 years' follow up

机译：XRCC1 rs25487基因变异和249位密码子的TP53突变可预测乙肝病毒相关性肝细胞癌切除术后的临床结局：一项为期10年的随访研究

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Aim: To investigate the effects of rs25487 (the DNA repair gene: x-ray repair complementing defective repair in Chinese hamster cells 1 [XRCC1]) and codon 249 mutation (TP53 gene) on clinical outcomes of post-hepatectomy hepatitis B virus (HBV)-related HCC.

机译：目的：研究rs25487（DNA修复基因：X射线修复补充中国仓鼠细胞1 [XRCC1]的缺陷修复）和249位密码子突变（TP53基因）对乙肝切除术后乙型肝炎病毒（HBV）临床结局的影响）相关的HCC。

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《Hepatology research: the official journal of the Japan Society of Hepatology》 |2016年第8期|共10页
作者
Yu Long; Liu Xiaoguang; Han Chuangye; Lu Sichong; Zhu Guangzhi; Su Hao; Qi Wei; Liao Xiwen; Peng Tao;
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正文语种 eng
中图分类消化系及腹部疾病;
关键词
codon 249; hepatitis B virus; hepatocellular carcinoma; prognosis; rs25487;

机译：密码子249;乙型肝炎病毒;肝细胞癌;预后;rs25487;

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外文文献

1. XRCC1 rs25487 genetic variant and TP53 mutation at codon 249 predict clinical outcomes of hepatitis B virus-related hepatocellular carcinoma after hepatectomy: A cohort study for 10 years' follow up [J] . Yu Long, Liu Xiaoguang, Han Chuangye, Hepatology research: the official journal of the Japan Society of Hepatology . 2016,第8期

机译：XRCC1 rs25487基因变异和249位密码子的TP53突变可预测乙肝病毒相关性肝细胞癌切除术后的临床结局：一项为期10年的随访研究
2. Hepatitis B 1762T/1764A mutations, hepatitis C infection, and codon 249 p53 mutations in hepatocellular carcinomas from Thailand. [J] . Kuang SY, Lekawanvijit S, Maneekarn N, Cancer epidemiology, biomarkers and prevention: A publication of the American Association for Cancer Research . 2005,第2期

机译：来自泰国的肝细胞癌中的乙型肝炎1762T / 1764A突变，丙型肝炎感染和249位p53密码子突变。
3. ATXN7 Gene Variants and Expression Predict Post-Operative Clinical Outcomes in Hepatitis B Virus-Related Hepatocellular Carcinoma [J] . Chuangye Han, Long Yu, Xiaoguang Liu, Cellular Physiology and Biochemistry . 2016,第6期

机译：ATXN7基因变异和表达预测乙型肝炎病毒相关肝细胞癌手术后的临床结果
4. Clinical Outcomes of Nucleoplasty: Prospective Cohort Study with Minimum of 2 Years Follow-up [C] . Boey J., Tow B., Yeo W., World Congress of Minimally Invasive Spine Surgery Techniques. . 2013

机译：核成形术的临床结果：未来队列研究，至少2年后续行动
5. Genome-wide association study of the TP53 R249S mutation in hepatocellular carcinoma with aflatoxin B1 exposure and infection with hepatitis B virus [O] . Chuangye Han, Tingdong Yu, Wei Qin, 2020

机译：肝炎B1肝细胞癌肝细胞癌TP53 R249S突变的基因组 - 宽协会研究及乙型肝炎病毒感染
6. TP53 R249S Mutations, Exposure to Aflatoxin, and Occurrence of Hepatocellular Carcinoma in a Cohort of Chronic Hepatitis B Virus Carriers from Qidong, China [O] . Szymanska, Katarzyna, Chen, Jian-Guo, Cui, Yan, 2009

机译：TP53 R249S突变，暴露于黄曲霉毒素和一组来自中国启东的慢性乙型肝炎病毒携带者的肝细胞癌

XRCC1 rs25487 genetic variant and TP53 mutation at codon 249 predict clinical outcomes of hepatitis B virus-related hepatocellular carcinoma after hepatectomy: A cohort study for 10 years' follow up

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