Asymmetric Catalysis of Homo-Coupling of 3-Substituted Naphthylamine and Hetero-Coupling with 3-Substituted Naphthol Leading to 3,3 '-Dimethyl-2,2 '-diaminobinaphthyl and-2-amino-2 '-hydroxybinaphthyl

摘要

Optically active 3,3'-dimethyl-2,2'-diamino-1,1'-binaphthyl (DM-DABN) and 3,3'-dimethyl-2-amino-2'-hydroxybinaphthyl (DM-NOBIN) derivatives were synthesized by Cu-(-)-sparteine complex-catalyzed enantioselective homo- and hetero-coupling of 2-naphthylamine, respectively. The difference in enantioselectivity was observed by changing the concentration of oxygen.