Synthesis, Structure and Antitumor Activities of [Ni(dien)_2][Ni(CN)_4] Complex

摘要

Ni(II)-dien complex was prepared and characterized by X-ray diffraction. The crystal belongs to triclinic system, space group P-l, with crystallographic parameters a= 0.888 13(18) nm, 6=0.890 10(18) nm, c = 1.591 8(3) nm, alpha=77. 71(3)°, beta=89.12(3)°, gamma=61. 24(3)°, Z=2. The two dien molecules coordinate to the central Ni atom, the six nitrogen atoms form a distorted octahedron. Preliminary pharmacological tests showed this complex had antitumor activity against HepG_2 and HL-60 cell linesin vitro.