Possible role of F18-FDG-PET/CT in differentiating benign lesions versus malignant after indeterminate fine-needle aspiration cytology. a wider and still controversial issue: exclusion of malignancy in thyroid nodules with indeterminate fine-needle aspiration cytology after negative 18F-fluorodeoxyglucose positron emission tomography: interim analysis.

摘要

An interesting article has recently been published in World Journal of Surgery [1] about the role of F18-fluorodeoxy-glucose positron emission tomography (FDG-PETC/CT) in indeterminate fine-needle aspiration cytology (FNAC) thyroid nodules, particularly in excluding malignancy. In the reported series, 51 patients with an indeterminate FNAC underwent F18-FDG-PETC/CT before thyroid surgery. For all lesions (10 malignant, 41 benign), the sensitivity, specificity, positive predictive value, and negative predictive value were 80, 61, 33, and 93%, respectively.