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Value of water-soluble contrast (meglumine amidotrizoate) in the diagnosis and management of small bowel obstruction.

机译:水溶性造影剂(葡甲胺三唑酸盐)在小肠梗阻的诊断和治疗中的价值。

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INTRODUCTION: The object of the present study was to determine the effectiveness of a water-soluble contrast follow-through study for differentiating complete from incomplete small bowel obstruction (SBO) and for predicting the need for surgery. METHODS: This prospective study was conducted at Riyadh Medical Complex, Saudi Arabia and spanned 2 years. All adult patients admitted with SBO were included, except those with obstructed hernias, peritonitis, or postabdominal irradiation. The initial resuscitation meglumine amidotrizoate (Gastrografin) follow-though was performed and was considered positive for complete obstruction if the contrast failed to reach the colon as shown on the 24-hour film. Patients were operated on only if they developed signs of strangulation or failed to improve within 48 hours. RESULTS: Our study group consisted of 73 patients, 48 (65.7%) of whom were male. The mean age was 35.70+/-12.65 years. In 60 (82.2%) patients, contrast reached the ascending colon within 24 hours, givinga definitive diagnosis of incomplete obstruction; among these 60 cases, 49 (81.7%) resolved on conservative management. The other 13 (17.8%) patients were diagnosed as having a complete obstruction; 4 (30.8%) of them were treated conservatively, and 9 (69.2%) underwent surgery. Therefore the sensitivity, specificity, positive predictive value, and negative predictive value for meglumine amidotrizoate follow-through as an indicator for operative treatment of SBO were 45.0, 92.5, 81.7, and 69.2, respectively. The P value using Fisher's exact test was 0.0006. CONCLUSIONS: We can confidently diagnose complete and incomplete SBO and differentiate one from the other. This accurate diagnosis indicates a high chance of success with conservative management for incomplete obstruction but does not always correlate with the need for surgical intervention.
机译:引言:本研究的目的是确定水溶性造影剂随访研究对区分完全性肠梗阻和不完全性小肠梗阻(SBO)以及预测手术需求的有效性。方法:这项前瞻性研究在沙特阿拉伯利雅得医疗中心进行,历时2年。除患有疝气阻塞,腹膜炎或腹部放射的患者外,所有接受SBO的成年患者均包括在内。进行了最初的复苏葡甲胺三唑酸酯(Gastrografin),如果造影剂未能到达结肠,则视为完全阻塞阳性,如24小时胶片所示。仅当患者出现绞窄迹象或在48小时内未能改善时才进行手术。结果:我们的研究组包括73例患者,其中48例(65.7%)为男性。平均年龄为35.70 +/- 12.65岁。在60名(82.2%)患者中,造影剂在24小时内到达上升结肠,从而明确诊断为不完全梗阻。在这60例病例中,有49例(81.7%)通过保守治疗得到解决。其他13名(17.8%)患者被诊断为完全阻塞;其中有4名(30.8%)接受了保守治疗,其中9名(69.2%)接受了手术。因此,氨甲三唑甲葡糖胺作为SBO手术治疗指标的敏感性,特异性,阳性预测值和阴性预测值分别为45.0、92.5、81.7和69.2。使用Fisher精确检验的P值为0.0006。结论:我们可以自信地诊断出完整和不完整的SBO,并可以彼此区分开。这种准确的诊断表明,对于不完全梗阻的保守治疗成功的可能性很高,但并不总是与手术干预的需求相关。

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