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Sprout branching of tumour capillary network growth: Fractal dimension and multifractal structure

机译:肿瘤毛细血管网络生长的新芽分支:分形维数和多重分形结构

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摘要

A tumour vascular network, characterized as an irregularly stochastic growth, is different from the normal vascular network. We systematically analyse the dependence of the branching. It is found that anastomosis of tumour on time is according to a number of tumour images, and both the fractal dimensions and multifractal spectra of the tumours are obtained. In the cases studied, the fractal dimensions of the tumour vascular network increase with time and the multifractal spectrum not only rises entirely but also shifts right. In addition, the best drug delivery stage is discussed according to the difference of the singularity exponent delta alpha(delta alpha = alpha(max) - alpha(min)), which shows some change in the growth process of the tumour vascular network. A common underlying principle is obtained from our analysis along with previous results.
机译:特征为不规则随机生长的肿瘤血管网络与正常血管网络不同。我们系统地分析了分支的依赖性。发现肿瘤按时吻合是根据许多肿瘤图像,并获得了肿瘤的分形维数和多重分形谱。在所研究的病例中,肿瘤血管网络的分形维数随时间增加,多重分形谱不仅完全上升,而且右移。此外,根据奇异指数Δalpha(Δalpha = alpha(max)-alpha(min))的差异讨论了最佳药物递送阶段,这表明肿瘤血管网络的生长过程发生了一些变化。从我们的分析以及先前的结果中得出了一个共同的基本原理。

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