Comparative study of mutations in SNP loci of K-RAS, hMLH1 and hMSH2 genes in neoplastic intestinal polyps and colorectal cancer

Yan Zhi-Hui; Cui Li-Hong; Wang Xiao-Hui; Li Chao; He Xing

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Comparative study of mutations in SNP loci of K-RAS, hMLH1 and hMSH2 genes in neoplastic intestinal polyps and colorectal cancer

机译：肿瘤性肠息肉和大肠癌K-RAS，hMLH1和hMSH2基因SNP位点突变的比较研究

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AIM: To clarify the molecular mechanism involved in pathogenesis of colorectal cancer as well as clinical significance of genetic analysis of histological samples.

机译：目的：阐明大肠癌发病机理的分子机制以及组织学样本遗传分析的临床意义。

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来源
《World journal of gastroenterology :》 |2014年第48期|共8页
作者
Yan Zhi-Hui; Cui Li-Hong; Wang Xiao-Hui; Li Chao; He Xing;
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正文语种 eng
中图分类消化系及腹部疾病;
关键词
Neoplastic intestinal polyp; Colorectal; cancer; Single nucleotide polymorphisms; K-RAS; hMLH1; hMSH2;

机译：肿瘤性肠息肉;结直肠;癌症;单核苷酸多态性;K-RAS;hMLH1;hMSH2;

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1. Comparative study of mutations in SNP loci of K-RAS, hMLH1 and hMSH2 genes in neoplastic intestinal polyps and colorectal cancer [J] . Yan Zhi-Hui, Cui Li-Hong, Wang Xiao-Hui, World journal of gastroenterology : . 2014,第48期

机译：肿瘤性肠息肉和大肠癌K-RAS，hMLH1和hMSH2基因SNP位点突变的比较研究
2. Prognostic significance of hMLH1/hMSH2 gene mutations and hMLH1 promoter methylation in sporadic colorectal cancer [J] . Wang Yibaina, Li Dandan, Li Xia, Medical oncology . 2014,第7期

机译：hMLH1 / hMSH2基因突变和hMLH1启动子甲基化在散发性结直肠癌中的预后意义
3. Sixteen rare sequence variants of the hMLH1 and hMSH2 genes found in a cohort of 254 suspected HNPCC (hereditary non-polyposis colorectal cancer) patients: mutations or polymorphisms? [J] . Muller-Koch Y, Kopp R, Lohse P, European journal of medical research. . 2001,第11期

机译：在254名可疑HNPCC（遗传性非息肉性结直肠癌）患者队列中发现的16种hMLH1和hMSH2基因罕见序列变异：突变或多态性？
4. Comparative analysis of p53 and K-ras gene mutations in gastric cancer tissue [C] . Aimei Zhang, Kun Sun, Rong Wang, International conference on biotechnology, chemical and materials engineering . 2012

机译：胃癌组织中p53和K-ras基因突变的比较分析
5. Insights Into the Mechanism of DNA Mismatch Repair Through a Biochemical Study of Cancer-Associated hMSH2-hMSH6 Mutations. [D] . Cyr, Jennifer Lynn. 2012

机译：通过与癌症相关的hMSH2-hMSH6突变的生化研究深入了解DNA错配修复的机制。
6. Comparative study of mutations in SNP loci of K-RAS hMLH1 and hMSH2 genes in neoplastic intestinal polyps and colorectal cancer [O] . Zhi-Hui Yan, Li-Hong Cui, Xiao-Hui Wang, 2014

机译：肿瘤性肠息肉和大肠癌K-RAShMLH1和hMSH2基因SNP位点突变的比较研究
7. Comparative study of mutations in SNP loci ofK-RAS,hMLH1andhMSH2genes in neoplastic intestinal polyps and colorectal cancer [O] . Zhi-Hui Yan 2014

机译：肿瘤肠息肉和结直肠癌突变型α-RAS，HMLH1ANDHMSH2GENES突变对比研究

Comparative study of mutations in SNP loci of K-RAS, hMLH1 and hMSH2 genes in neoplastic intestinal polyps and colorectal cancer

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