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Cost-effectiveness of protocols for diagnosis of bovine tuberculosis in a naturally infected herd

机译:天然感染牛群中牛结核病诊断方案的成本效益

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摘要

In several countries, bovine tuberculosis, caused by Mycobacterium bovis, is an economic and public health problem. Worldwide disease eradication programs are implemented with policies based on tuberculin testing and slaughter of reactive animals. However, little is known about the costs and the effectiveness of the eradication policies. We evaluated the cost-effectiveness of bovine tuberculosis diagnostic protocols on a multidisciplinary approach, applied in a naturally infected herd. Regarding the cost-effectiveness analysis (C/Ef) of ante-mortem diagnostic protocols, the Cervical Comparative Test (C/Ep=4.68), when used alone, is the diagnostic protocol most cost-effective for a naturally infected herd. For post-mortem confirmatory diagnostic, the histopathology (C/Ep=17.47) associated with the Cervical Simple Test and Cervical Comparative Test was the most cost-effective choice for the animals studied in this herd. However, the only diagnostic protocol that was able to identify 100% of the infected animals was the ELISA associated with the IFN test.
机译:在一些国家,牛分枝杆菌引起的牛结核病是经济和公共卫生问题。全球根除疾病的计划是根据结核菌素测试和屠宰反应性动物的政策实施的。但是,对于根除政策的成本和有效性知之甚少。我们采用多学科方法评估了牛结核诊断方案的成本效益,该方法适用于自然感染的牛群。关于事前诊断规程的成本效益分析(C / Ef),当单独使用宫颈比较试验(C / Ep = 4.68)时,对于自然感染牛群而言,该诊断规程最具成本效益。对于验尸确认性诊断,与宫颈简单试验和宫颈比较试验相关的组织病理学(C / Ep = 17.47)是该畜群中研究的最具成本效益的选择。但是,唯一能够确定100%受感染动物的诊断方案是与IFN测试相关的ELISA。

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