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Atherosclerosis in the Renaissance elite: Ferdinand I King of Naples (1431-1494).

机译:文艺复兴时期精英时期的动脉粥样硬化:那不勒斯国王费迪南德一世(1431-1494)。

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Atherosclerosis is often considered a modern disease, associated with contemporary lifestyle; however, vascular calcifications and plaques have been identified in ancient human remains, mainly in the Egyptian mummies of people belonging to the elite classes [1,2].Various factors have been considered in the pathogenesis of atherosclerosis, including genetic predisposition and environmental factors such as obesity, exposure to smoke and composition of diet that is rich in cholesterol and saturated fats [3].The mummy of Ferrante I of Aragon (1431-1494), King of Naples and one of the most important personalities of the Italian Renaissance, was exhumed from its sarcophagus in the monumental sacristy of the Basilica of San Domenico Maggiore in Naples (southern Italy). The dry microclimatic conditions of the church, where several mummies of Renaissance Aragonese princes and noblemen are preserved, as well as the substances used for embalming, favored an excellent state of preservation of soft tissues and internal organs.
机译:动脉粥样硬化常被认为是与现代生活方式有关的现代疾病。然而,在古代人类遗骸中已经发现了血管钙化和斑块,主要是在埃及精英阶层的木乃伊中[1,2]。在动脉粥样硬化的发病机理中考虑了各种因素,包括遗传易感性和环境因素,例如肥胖,烟熏以及富含胆固醇和饱和脂肪的饮食组成[3]。阿拉贡的Ferrante I(1431-1494)的木乃伊,那不勒斯国王,意大利文艺复兴时期最重要的人物之一,在那不勒斯(意大利南部)的圣多梅尼科·马焦雷大教堂的纪念性圣殿中从其石棺中挖出。教堂处于干燥的微气候条件,那里保存着几座文艺复兴时期阿拉贡王子和贵族的木乃伊,以及用于防腐的物质,有利于软组织和内脏器官的良好保存状态。

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