Synthesis of an anthrose derivative and production of polyclonal antibodies for the detection of anthrax spores

摘要

A straightforward synthesis of a derivative of anthrose, the non-reducing terminal fragment of the antigenic tetrasaccharide from Bacillus anthracis, was achieved starting from D-galactose. This hapten is able to induce a highly specific and sensitive immune response in rabbit when attached to a carrier protein. (C) 2007 Elsevier Ltd. All rights reserved.