Asymmetric organocatalysis with glycosyl-beta-amino acids:direct asymmetric aldol reaction of acetone with aldehydes

摘要

Direct asymmetric aldol reaction of acetone with aromatic aldehydes was achieved in good yields and high enantioselec-tivity using 5-amino-5-deoxy-beta-L-ido-(alpha-D-glwco)-heptofuranuronic acids as a new class of organocatalysts.