Mean central corneal thickness and corneal power measurements in pigmented and white rabbits using Visante optical coherence tomography and ATLAS corneal topography.

摘要

Objective: To document central corneal thickness (CCT) and power measurements in pigmented and white rabbits using Visante anterior segment optical coherence tomography (AS-OCT) and the Humphrey ATLAS Corneal Topography System (HACTS). Animal studied: Fourteen female rabbits (seven pigmented and seven white rabbits) were involved in this study. Procedure: Twenty-eight eyes underwent AS-OCT and HACTS examination. Central corneal thickness, corneal power in the steepest and flattest meridians, astigmatism, pupil diameter (PD), and white-to-white (WTW) were calculated. Results: The CCT was 390+or-14.2 and 373+or-7.2 micro m for pigmented and white rabbits, respectively. The CCT values showed statistical difference between the two breeds (P=0.017). The corneal power in the steepest meridian was 44.6+or-1.9 Diopter (D) in pigmented rabbits and 47.8+or-1.5 D in white rabbits. The corneal power in the flattest meridian was 44.0+or-2.1 D in pigmented rabbits and 47.4+or-1.5 D in white rabbits. The astigmatism, PD, and WTW values were 0.6+or-0.22 D, 7.9+or-0.9, and 14.5+or-0.1 mm in pigmented rabbits, respectively. The corresponding values in white rabbits were 0.4+or-0.23 D, 7.5+or-0.5, and 13.5+or-0.2 mm. There was a statistically significant difference in corneal power in the steepest and flattest meridians and for WTW. No such difference was observed for astigmatism or PD between them. Conclusions: Differences exist in the CCT, corneal power, and WTW between 5-month-old pigmented and white rabbits. Such difference should be considered when designing cornea-related experiments in rabbits.