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Testing for vector-borne pathogens in dogs: the best use of diagnostic panels

机译:测试犬中的媒介传播病原体:诊断板的最佳用途

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摘要

Serologic and PCR panels can help identify infection with vector-borne disease agents. So which panel should youchoose Maybe both.Most serologic tests document infection indirectly bydetecting antibodies to the infectious agent. Demonstrating the presence of antibody indicates exposure but does not necessarily indicate active infection.PCR makes it possible to directly test for the presence of multiple organisms with high sensitivity and specificity, assuming appropriate laboratory controls are in place. However, organisms are not always circulating in blood in high enough numbers to be present in a blood sample at the time clinical signs occur.
机译:血清学和PCR检测板可以帮助鉴定媒介传播的疾病媒介物的感染。因此,大多数情况下,血清学检测都是通过检测感染因子的抗体间接证明感染。证明抗体的存在表明已暴露,但未必表明发生了主动感染。PCR使在适当的实验室控制前提下,可以高灵敏度和特异性直接检测多种生物的存在。但是,生物体并不总是在血液中循环大量,以至于在出现临床体征时就存在于血液样本中。

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