SDMA pinpointed as biomarkerfor early diagnosis of feline renal disease

摘要

Chronic kidney disease in cats is often not recognized in the clinical setting until there is evidence of azotemia and loss of urine concentrating ability. Identification of sensitive serum biomark-ers, which would allow early identification of cats with renal disease, would facilitate early intervention and improve patient care. Symmetric dimethylargi-nine (SDMA) has been found to be an accurate surrogate for estimated glomerular filtration rate (GFR) in people and a more sensitive biomarker of renal function. These studies sought to evaluate the utility of this biomarker in the setting of feline renal disease.