Mast cell tumours in dogs:Kathryn Marguerite Pratschke MVB MVM CertSAS DiplECVS MRCVS

摘要

Mast cell tumours (MCTs) are a commonly encountered skin neoplasm in dogs. A study of over one million dogs from the US o in 2011 described MCTs as the thid most common cutaneous malignancy at 11% of the total. In the UK, MCT is the second most commoncanine malignancy (soft tissue sarcoma being the most common), with an incidence of 129 per 100,000 insured dogs per year. MCTs are typically seen in older dogs, ranging between 7.5-10 years, and the most commonly affected breeds include Boxers, Labradors, Rhodesian Ridgebacks, Viszlas, Boston terriers, mixed breed dogs and Weimaraners. There is no strong or consistent gender predilection.3-4 Most MCTs present as single lesions, but the phenomenon of adjacent cutaneous satellite lesions (also called locoregional metastases) is well recognised, as is that of patients developing multiple de novo MCTs.5 MCTs are most commonly cutaneous or subcutaneous in origin, occasionally visceral, and with an intramuscular variant also recently described.