Structural studies of the antigen III cell wall polysaccharide of Trichosporon domesticum

摘要

Cell wall and soluble polysaccharides that reaacted with Trichosporon domestiicum factor III serum were isolated form the type strain of T. domesticum. The fractions contained O-acetyl groups, which contributed to the serological reactivity. The antigenic structure was characterized by chromatographic and spectroscopic methods. The polysaccharide has an #alpha#-(1->3)-D-mannan backbone with hetero-oligosaccharide side chains consisting of a 2-O-substituted #beta#-D-glucuronic acid residue bound to O-2 of the mannose residue, #beta#-D-xylopyranosyl residues located in the middle of the side chian, and a nonreducing terminal #alpha#-L-arabinopyransoyl residue bound to O-4 of xylose. The mannan backbone is O-acetylated at O-6 of the mannose residues.