There are several approaches to quantifying the contribution of medicinal drug use to road accidents. These include, among others, case-control studies, correlational studies (where the relationship between variables describing medicinal drug use and accident involvement is estimated) and responsibility analysis (where drivers are classified as culpable, contributory or not culpable on the basis of several factors, and then related to the presence or not of the substance in their biological fluids). As Ramaekers has pointed out in his letter to TiPS [1] in response to our recent TiPS article [2] case-control studies are the most powerful tools to determine the causal relationship between medicinal drug use and road accidents.
展开▼
