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Estimating the impact of unsafe water, sanitation and hygiene on the global burden of disease: Evolving and alternative methods

机译:估计不安全的水,卫生设施和卫生设施对全球疾病负担的影响:不断发展的替代方法

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The 2010 global burden of disease (GBD) study represents the latest effort to estimate the global burden of disease and injuries and the associated risk factors. Like previous GBD studies, this latest iteration reflects a continuing evolution in methods, scope and evidence base. Since the first GBD Study in 1990, the burden of diarrhoeal disease and the burden attributable to inadequate water and sanitation have fallen dramatically. While this is consistent with trends in communicable disease and child mortality, the change in attributable risk is also due to new interpretations of the epidemiological evidence from studies of interventions to improve water quality. To provide context for a series of companion papers proposing alternative assumptions and methods concerning the disease burden and risks from inadequate water, sanitation and hygiene, we summarise evolving methods over previous GBD studies. We also describe an alternative approach using population intervention modelling. We conclude by emphasising the important role of GBD studies and the need to ensure that policy on interventions such as water and sanitation be grounded on methods that are transparent, peer-reviewed and widely accepted.
机译:2010年全球疾病负担(GBD)研究代表了估算疾病和伤害的全球负担以及相关风险因素的最新努力。像以前的GBD研究一样,此最新迭代反映了方法,范围和证据基础的不断发展。自1990年进行首次GBD研究以来,腹泻病的负担以及因水和卫生设施不足而引起的负担已大大下降。虽然这与传染病和儿童死亡率的趋势一致,但归因风险的变化也归因于对改善水质的干预研究对流行病学证据的新解释。为了提供一系列伴随论文的背景,这些论文提出了关于水,卫生和卫生条件不足造成的疾病负担和风险的替代性假设和方法,我们总结了以往GBD研究中不断发展的方法。我们还描述了使用人口干预模型的另一种方法。最后,我们着重强调GBD研究的重要作用以及确保以透明,经过同行评审和广泛接受的方法为基础的水和卫生等干预政策的必要性。

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