Assessing the frequencies of GP.Mur (Mi.III) in several Southeast Asian populations by PCR typing

摘要

In the fields of transfusion medicine and blood banking, the special red cell phenotype GP.Mur (also known as Mil-tenberger type III, Mi.III) is gradually recognized to be one of the most important blood types in Taiwan and many other Southeast Asian countries [1]. In early days, GP.Mur was serologically defined and classified with 10 other gly-cophorin variants in the Miltenberger series of the MNS blood group system [2,3]. It is now clear that these 11 gly-cophorin variants in the Miltenberger series (initially termed Mi.I to Mi.XI) were evolved from gene recombination events between homologous glycophorin A and gly-cophorin B, and are thus associated with one another in terms of their protein structures and serological activities.