The traditional approach to experimentation,often referred to as the"scientific method,"requires changing only one factor at a time(OFAT).This should not be confused with the full fac-torial method(Tablel).These approaches not only suffer from being extremely inefficient,but more importantly,they cannot detect interactions of factors - much less map complex response surfaces.For example,consider the effects of two factors"A"and"B",such as temperature and pressure,on a response - for example,chemical yield.Let's say these factors affect the response as shown by the surface in Figure 1.
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