Don't get steamed by sterilization

摘要

SINCE 1978,I'VE BEEN DESIGNING PROCESSES,when I helped develop a successful new pharmaceutical route. Later,I spent five years in a pilot plant which ran more than 100 fermenters. Throughout this time,I have had to grapple with steam sterilization issues and have found that while the principles of steam sterilization are well known,designing actual systems can pose big challenges.