The current study summarizes clinical findings and treatment of cats with permethrin intoxication presented at the Small Animal Clinic of the University of Veterinary Medicine, Hannover, Germany, between 2002 and 2005. Ten cats were topically treated by their owners with a spot-on permethrin product designated for dogs. Signalement, signs, course of the disease and treatment are described. Nine Domestic Shorthair cats and one Siamese cat with a median age of 4.75 years and a median body weight of 5 kg were affected. The owners recognized the first signs after 2-24 h. The median duration of symptoms was 30 h and included tremors, mydriasis, generalized seizures, tachycardia, hyperthermia and ventricular extrasystoles. Treatment consisted of rinsing with detergents, clipping, maintenance of normal body temperature and treatment of seizures and tremor with diazepam, phenobarbital and/or pentobarbital. One animal was euthanized on the owner's request. The remaining 9 cats were discharged without any symptoms after 2-9 days. With early and symptomatic treatment, the prognosis of permethrin intoxication in cats is good..
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