Thrombotic safety of prothrombin complex concentrate (Beriplex P/N) for dabigatran reversal in a rabbit model.

Eva Herzog; Franz J Kaspereit; Wilfried Krege; Baerbel Doerr; Joanne van Ryn; Gerhard Dickneite; Ingo Pragst

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Thrombotic safety of prothrombin complex concentrate (Beriplex P/N) for dabigatran reversal in a rabbit model.

机译：凝血酶原复合物浓缩物（Beriplex P / N）对达比加群逆转在兔模型中的血栓安全性。

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In this animal study, thrombosis after PCC administration could be prevented in the presence of dabigatran. PCC reversed dabigatran-induced excessive bleeding while retaining protective anticoagulatory activity of dabigatran.

机译：在这项动物研究中，在达比加群存在的情况下，可以预防PCC给药后的血栓形成。 PCC逆转了达比加群引起的大量出血，同时保留了达比加群的保护性抗凝活性。

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《Thrombosis Research: An International Journal on Vascular Obstruction, Hemorrhage and Hemostasis》 |2014年第3期|共8页
作者
Eva Herzog; Franz J Kaspereit; Wilfried Krege; Baerbel Doerr; Joanne van Ryn; Gerhard Dickneite; Ingo Pragst;
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正文语种 eng
中图分类神经病学;
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1. Thrombotic safety of prothrombin complex concentrate (Beriplex P/N) for dabigatran reversal in a rabbit model. [J] . Eva Herzog, Franz J Kaspereit, Wilfried Krege, Thrombosis Research: An International Journal on Vascular Obstruction, Hemorrhage and Hemostasis . 2014,第3期

机译：凝血酶原复合物浓缩物（Beriplex P / N）对达比加群逆转在兔模型中的血栓安全性。
2. Four-factor prothrombin complex concentrate (Beriplex? P/N) is superior to three-factor prothrombin complex concentrate for reversal of coumarin anticoagulation [J] . E Herzog, F Kaspereit, W Krege, Critical care : . 2015,第Suppla1期

机译：四因子凝血酶原复合物浓缩物（Beriplex？P / N）在逆转香豆素抗凝方面优于三因子凝血酶原复合物浓缩物
3. Prothrombin complex concentrate (Beriplex P/N) for control of bleeding after kidney trauma in a rabbit dilutional coagulopathy model. [J] . Pragst I, Kaspereit F, Dorr B, Thrombosis Research: An International Journal on Vascular Obstruction, Hemorrhage and Hemostasis . 2010,第3期

机译：在兔稀释性凝血病模型中，凝血酶原复合物浓缩物（Beriplex P / N）用于控制肾脏外伤后的出血。
4. Reversal of Warfarin-Associated Coagulopathy: Prothrombin Complex Concentrates Versus Fresh Frozen Plasma in Elderly Patients Presenting with Intracranial Hemorrhage [D] . Lumas, Shunella Grace. 2020

机译：逆转华法林相关凝血病：凝血酶原浓缩物与颅内出血患者的老年患者新鲜冷冻血浆
5. Four-factor prothrombin complex concentrate (Beriplex® P/N) is superior to three-factor prothrombin complex concentrate for reversal of coumarin anticoagulation [O] . E Herzog, F Kaspereit, W Krege, 2015

机译：四因子凝血酶原复合物浓缩物（Beriplex®P / N）在逆转香豆素抗凝方面优于三因子凝血酶原复合物浓缩物
6. Thrombotic safety of prothrombin complex concentrate (Beriplex P/N) for dabigatran reversal in a rabbit model [O] . Herzog Eva, Kaspereit Franz J., Krege Wilfried, 2014

机译：凝血酶原复合物浓缩物（Beriplex P / N）对达比加群逆转兔模型的血栓安全性

Thrombotic safety of prothrombin complex concentrate (Beriplex P/N) for dabigatran reversal in a rabbit model.

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