Reliability of thromboelastometry for detecting the safe coagulation threshold in patients taking acenocoumarol after elective heart valve replacement

Blasi Annabel; Munoz Guido; de Soto Ines; Mellado Ricard; Taura Pilar; Rios Jose; Balust Jaume; Beltran Joan

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Reliability of thromboelastometry for detecting the safe coagulation threshold in patients taking acenocoumarol after elective heart valve replacement

机译：选择性心脏瓣膜置换术后服用乙酰香豆酚的血栓弹力法检测安全凝结阈值的可靠性

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Background: Reversal of anticoagulation can be needed in patients undergoing heart valve surgery. ROTEM (R) has been correlated with international normalized ratio (INR) in patients on warfarin but not with patients on acenocoumarol. This study investigates the reliability of ROTEM (R) for detecting INR values below the 1.5 threshold in patients on acenocoumarol therapy.

机译：背景：进行心脏瓣膜手术的患者可能需要逆转抗凝治疗。在使用华法令的患者中，ROTEM（R）与国际标准化比率（INR）相关，但与乙酰香豆酚的患者无关。这项研究调查了ROTEM（R）在接受乙酰香豆酚治疗的患者中检测INR值低于1.5阈值的可靠性。

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《Thrombosis Research: An International Journal on Vascular Obstruction, Hemorrhage and Hemostasis 》 |2015年第3期| 共4页
作者
Blasi Annabel; Munoz Guido; de Soto Ines; Mellado Ricard; Taura Pilar; Rios Jose; Balust Jaume; Beltran Joan;
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正文语种 eng
中图分类神经病学 ;
关键词
thromboelastometry; acenocumarol;

机译：血栓弹力测定;醋马酚;

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1. Reliability of thromboelastometry for detecting the safe coagulation threshold in patients taking acenocoumarol after elective heart valve replacement [J] . Blasi Annabel, Munoz Guido, de Soto Ines, Thrombosis Research: An International Journal on Vascular Obstruction, Hemorrhage and Hemostasis . 2015 ,第3期

机译：选择性心脏瓣膜置换术后服用乙酰香豆酚的血栓弹力法检测安全凝结阈值的可靠性
2. Cytochrome P450 (CYP2C9*2,*3) & vitamin-K epoxide reductase complex (VKORC1 -1639G < A) gene polymorphisms & their effect on acenocoumarol dose in patients with mechanical heart valve replacement [J] . Anupriya Kaur, Farah Khan, Suraksha S Agrawal, The Indian journal of medical research . 2013 ,第1期

机译：机械心脏瓣膜置换患者的细胞色素P450（CYP2C9 * 2，* 3）和维生素K环氧还原酶复合物（VKORC1 -1639G
3. A comparison of dabigatran etexilate with warfarin in patients with mechanical heart valves: The Randomized, phase II study to Evaluate the sAfety and pharmacokinetics of oraL dabIGatran etexilate in patients after heart valve replacemeNt (RE-ALIGN) [J] . VanDeWerfF., BrueckmannM., ConnollyS.J., The American heart journal . 2012 ,第6期

机译：机械性心脏瓣膜病患者中达比加群酯与华法林的比较：随机II期研究评估心脏瓣膜置换术后患者口服达比格仑酯的安全性和药代动力学（RE-ALIGN）
4. PATIENT-SPECIFIC THREE-DIMENSIONAL COMPUTATIONAL HEART MODELING AND PRINTING TO ENHANCE CLINICAL UNDERSTANDINGS AND TREATMENT PLANNING: CONGENITAL RECURRENT PULMONARY ARTERY STENOSIS AND TRANSCATHETER PULMONARY VALVE REPLACEMENT [C] . Amanda C. Tenhoff, Varun Aggarwal, Rebecca Ameduri, Design of Medical Devices Conference . 2021

机译：患者特异性三维计算心脏建模和印刷，增强临床谅解和治疗计划：先天性复发性肺动脉狭窄和经导管肺瓣膜置换
5. Novel cardiovascular anticoagulation for thromboprophylaxis of mechanical heart valves in a porcine model of heterotopic valve replacement. [D] . Greiten, Lawrence Edward. 2016

机译：在异位瓣膜置换的猪模型中，新型心血管抗凝剂可预防机械性心脏瓣膜的血栓形成。
6. Cytochrome P450 (CYP2C9*2*3) vitamin-K epoxide reductase complex (VKORC1 -1639GA) gene polymorphisms their effect on acenocoumarol dose in patients with mechanical heart valve replacement [O] . Anupriya Kaur, Farah Khan, Suraksha S. Agrawal, 2013

机译：机械心脏瓣膜置换术患者细胞色素P450（CYP2C9 * 2* 3）和维生素K环氧还原酶复合物（VKORC1 -1639G A）基因多态性及其对乙酰香豆酚剂量的影响
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机译：通过心音描记术分析金属心脏瓣膜置换患者的病例随访研究。

Reliability of thromboelastometry for detecting the safe coagulation threshold in patients taking acenocoumarol after elective heart valve replacement

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