Assessing the anticoagulant effect of dabigatran in children: An in vitro study

Dietrich Kevin; Stang Linda; van Ryn Joanne; Mitchell Lesley G.

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Assessing the anticoagulant effect of dabigatran in children: An in vitro study

机译：评估达比加群对儿童的抗凝作用：一项体外研究

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Objectives: Age-related changes in the hemostatic system result in variation in response to anticoagulants and coagulation assays over childhood. This study used in vitro methods to determine i) optimum coagulation assays for dabigatran in children and ii) anticoagulant effect of dabigatran across pediatric age groups.

机译：目的：随着年龄的增长，止血系统的变化会导致儿童期对抗凝剂和凝血测定的反应发生变化。这项研究使用体外方法确定i）儿童达比加群的最佳凝血测定，以及ii）跨年龄段儿童的达比加群的抗凝作用。

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《Thrombosis Research: An International Journal on Vascular Obstruction, Hemorrhage and Hemostasis》 |2015年第4期|共6页
作者
Dietrich Kevin; Stang Linda; van Ryn Joanne; Mitchell Lesley G.;
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正文语种 eng
中图分类神经病学;
关键词
Pediatric; Dabigatran etexilate; Direct thrombin inhibitor; Coagulation assays; In vitro; Novel oral anticoagulants;

机译：儿科;达比加群酯;直接凝血酶抑制剂;凝血测定;体外;新型口服抗凝药;

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1. Assessing the anticoagulant effect of dabigatran in children: An in vitro study [J] . Dietrich Kevin, Stang Linda, van Ryn Joanne, Thrombosis Research: An International Journal on Vascular Obstruction, Hemorrhage and Hemostasis . 2015,第4期

机译：评估达比加群对儿童的抗凝作用：一项体外研究
2. Usefulness of multidetector CT imaging to assess vascular stents in children with congenital heart disease: an in vivo and in vitro study. [J] . Eichhorn JG, Long FR, Jourdan C, Catheterization and cardiovascular interventions: Official journal of the Society for Cardiac Angiography & Interventions . 2008,第4期

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机译：多探测器CT成像对评估先天性心脏病患儿血管支架的有用性：一项体内和体外研究。
4. Application of Humic Substances in Medicine: Basic Studies to Assess Pro-and Anticoagulant Properties of Humic Acids [C] . H.P. Klocking, R. Klocking The Meeting of the International Humic Substances Society . 2013

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6. Idarucizumab for Emergency Reversal of Anticoagulant Effects of Dabigatran: Interim Results of a Japanese Post-Marketing Surveillance Study [O] . Masahiro Yasaka, Hiroyuki Yokota, Michiyasu Suzuki, 2020

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7. Assessing the anticoagulant effect of dabigatran in children: An in vitro study [O] . Dietrich Kevin, Stang Linda, van Ryn Joanne, 2015

机译：评估达比加群对儿童的抗凝作用：一项体外研究

Assessing the anticoagulant effect of dabigatran in children: An in vitro study

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