What is the true risk of bleeding when cooling patients to 33 degrees Celsius?

摘要

Mild hypothermia can result in a mild coagulopathy. At temperatures less than 35°C, platelet dysfunction and decreases in platelet counts can be seen, and in temperatures less than 33°C, an effect may also be seen on the synthesis and kinetics of clotting enzymes and plasminogen activator inhibitors. The effects of hypothermia on coagulation and platelet function are influenced by