Relationship Between Plasma Concentrations of Lamotrigine and Its Early Therapeutic Effect of Lamotrigine Augmentation Therapy in Treatment-Resistant Depressive Disorder

Kagawa Shoko; Mihara Kazuo; Nakamura Akifumi; Nemoto Kenji; Suzuki Takeshi; Nagai Goyo; Kondo Tsuyoshi

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Relationship Between Plasma Concentrations of Lamotrigine and Its Early Therapeutic Effect of Lamotrigine Augmentation Therapy in Treatment-Resistant Depressive Disorder

机译：拉莫三嗪的血浆浓度与其抗抑郁药治疗中拉莫三嗪增强疗法的早期治疗效果之间的关系

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Background: The relationship between plasma concentrations of lamotrigine and its therapeutic effects was prospectively studied on 34 (9 men and 25 women) inpatients with treatment-resistant depressive disorder during an 8-week treatment of lamotrigine augmentation using an open-study design.

机译：背景：使用开放性研究设计，对34名（9名男性和25名女性）住院治疗难治性抑郁症患者进行了为期8周的拉莫三嗪增强治疗，对拉莫三嗪血浆浓度与其治疗效果之间的关系进行了前瞻性研究。

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来源
《Therapeutic Drug Monitoring》 |2014年第6期|共4页
作者
Kagawa Shoko; Mihara Kazuo; Nakamura Akifumi; Nemoto Kenji; Suzuki Takeshi; Nagai Goyo; Kondo Tsuyoshi;
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正文语种 eng
中图分类生药学（天然药物学）;
关键词
lamotrigine; plasma concentration; augmentation therapy; treatment-resistant; early response;

机译：拉莫三嗪;血浆浓度;增强疗法;抗治疗;早期反应;

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1. Relationship Between Plasma Concentrations of Lamotrigine and Its Early Therapeutic Effect of Lamotrigine Augmentation Therapy in Treatment-Resistant Depressive Disorder [J] . Kagawa Shoko, Mihara Kazuo, Nakamura Akifumi, Therapeutic Drug Monitoring . 2014,第6期

机译：拉莫三嗪的血浆浓度与其抗抑郁药治疗中拉莫三嗪增强疗法的早期治疗效果之间的关系
2. Prediction of an Optimal Dose of Lamotrigine for Augmentation Therapy in Treatment-Resistant Depressive Disorder From Plasma Lamotrigine Concentration at Week 2 [J] . Nakamura Akifumi, Mihara Kazuo, Nagai Goyo, Therapeutic Drug Monitoring . 2016,第3期

机译：从第2周血浆Lamotrigine浓度预测用于治疗抗抑郁性抑郁症的增强疗法拉莫三嗪的最佳剂量
3. Both Serum Brain-Derived Neurotrophic Factor and Interleukin-6 Levels Are Not Associated with Therapeutic Response to Lamotrigine Augmentation Therapy in Treatment-Resistant Depressive Disorder [J] . Kagawa Shoko, Mihara Kazuo, Suzuki Takeshi, Neuropsychobiology . 2017,第3期

机译：血清脑衍生的神经营养因子和白细胞介素-6水平与治疗抗性抑郁症的乳芳素增强治疗的治疗反应无关
4. Toward the Precision Medicine for a Psychiatric Disorder: Light Therapy for Major Depressive Disorder with Neuroimaging Validation [C] . Fan-pei Gloria Yang, Wei-cheng Chao, Sung-wei Chen International Conference on Biomedical and Health Informatics . 2020

机译：对精神疾病进行精密药物：对神经影像学验证的主要抑郁障碍的光疗
5. Psychological flexibility, rumination, and avoidance as predictors of outcome in cognitive behavioral therapy for treatment-resistant major depressive disorder [D] . Yasinski, Charlotte Wood. 2016

机译：心理柔韧性，反省和回避可作为耐行为性重度抑郁症认知行为疗法预后的指标
6. Lamotrigine Augmentation of Serotonin Reuptake Inhibitors in Severe and Long-Term Treatment-Resistant Obsessive-Compulsive Disorder [O] . Manuel Arrojo-Romero, María Tajes Alonso, Jose de Leon 2013

机译：重度和长期抗药性强迫症中5-羟色胺再摄取抑制剂的拉莫三嗪增强
7. Lamotrigine augmentation therapy in a case with treatment-resistant unipolar depression that showed insufficient response to electroconvulsive therapy [O] . Kazuo Mihara, Akifumi Nakamura, Kenji Nemoto, 2016

机译：在耐治疗的单极性抑制的情况下，乳芳素增强疗法表现出对电吞咽治疗的反应不足

Relationship Between Plasma Concentrations of Lamotrigine and Its Early Therapeutic Effect of Lamotrigine Augmentation Therapy in Treatment-Resistant Depressive Disorder

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