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The future of veterinary therapeutics: A glimpse towards 2030

机译:兽医疗法的未来:2030年的一瞥

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摘要

The purpose of this article is to make an educated guess as to what veterinary pharmacology will look like in two decades. By examining the past, it is evident that change is incremental unless a transforming discovery occurs. In the last few decades, such events have dramatically changed medicine and pharmacology, however they have not percolated through the system to the effect that novel drugs have replaced our traditional armamentarium. The effect of six transforming technologies (continued advances in computer technology, microfluidics, nanotechnology, high-throughput screening, control and targeted drug delivery, pharmacogenomics) on veterinary therapeutics is examined. These should lead toward more efficacious and safer drugs across most therapeutic classes due to both increases in our knowledge base as well as more efficient drug development. Shorter term improvements in drug delivery should be seen. Although this growth in technology would portend major advances over the next few decades, economic and regulatory constraints must still be overcome for these new drugs or therapeutic approaches to become common practice.
机译:本文的目的是对二十年后的兽医药理学进行有根据的猜测。通过回顾过去,很明显,除非发生转变的发现,否则变化是渐进的。在过去的几十年中,此类事件极大地改变了医学和药理学,但并未渗透到整个系统中,以致新药已取代了我们的传统军械库。研究了六种转化技术(计算机技术,微流体技术,纳米技术,高通量筛选,控制和靶向药物递送,药物基因组学的不断进步)对兽医治疗的影响。由于我们知识库的增加以及药物开发的效率提高,这些方法将导致大多数治疗类别中的药物更加有效和安全。应该看到药物输送的短期改善。尽管这种技术的增长将预示未来几十年将取得重大进展,但对于这些新药或治疗方法而言,要成为普遍的实践,仍必须克服经济和监管方面的限制。

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