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首页> 外文期刊>The Veterinary Record >Anaesthesia with sevoflurane in pigeons: minimal anaesthetic concentration (MAC) determination and investigation of cardiorespiratory variables at 1 MAC
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Anaesthesia with sevoflurane in pigeons: minimal anaesthetic concentration (MAC) determination and investigation of cardiorespiratory variables at 1 MAC

机译:七氟醚在鸽子中的麻醉:最低麻醉浓度(MAC)测定和1 MAC时的心肺变量研究

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The objective of the study was to determine the minimal anaesthetic concentration (MAC) of sevoflurane (SEVO) in pigeons and investigate the effects of 1 MAC SEVO anaesthesia on cardiovascular and respiratory variables compared with the awake state. This is a prospective, experimental study. Animals were seven healthy adult pigeons. After acclimatisation to handling, heart rate (HR), heart rhythm, respiratory rate (fR), end-expired carbon dioxide tension (PE'CO2), inspired CO2 tension, indirect systolic arterial blood pressure (SAP) and cloacal temperature were measured to determine baseline, 'awake' values. Pigeons were then anaesthetised with SEVO and MAC was determined by the 'bracketing' method. The same variables were monitored during a 40 minute period at 1.0 MAC SEVO for each bird. Mean MAC was 3.0+/-0.6 per cent for SEVO. During maintenance of anaesthesia at 1.0 MAC, SAP decreased significantly (P<0.001) without any significant change in HR. Although PE'CO2 increased significantly (P=0.001) despite an increase in fR, awake PE'CO2 values were unexpectedly low. Sinus arrhythmias were detected in two birds under SEVO anaesthesia. The times to tracheal intubation and to recovery were 2.5+/-0.7 and 6.4+/-1.7 minutes, respectively. Recovery was rapid and uneventful in all birds. In conclusion, SEVO is suitable for anaesthesia in pigeons.
机译:该研究的目的是确定鸽子中七氟醚(SEVO)的最低麻醉浓度(MAC),并研究1 MAC SEVO麻醉与清醒状态相比对心血管和呼吸系统变量的影响。这是一项前瞻性实验研究。动物是七只健康的成年鸽子。适应操作后,测量心率(HR),心律,呼吸频率(fR),呼气末二氧化碳张力(PE'CO2),吸入二氧化碳张力,间接收缩动脉血压(SAP)和泄殖腔温度确定基线“清醒”值。然后用SEVO麻醉鸽子,并通过“包围”法确定MAC。在40分钟内以每只鸟1.0 MAC SEVO监视相同的变量。 SEVO的平均MAC为3.0 +/- 0.6%。在以1.0 MAC维持麻醉期间,SAP显着下降(P <0.001),而HR没有任何显着变化。尽管尽管fR增加,但PE'CO2仍显着增加(P = 0.001),但清醒的PE'CO2值出乎意料地低。在SEVO麻醉下,在两只鸟中发现窦性心律不齐。气管插管和恢复的时间分别为2.5 +/- 0.7分钟和6.4 +/- 1.7分钟。所有鸟类的恢复都很迅速,也很顺利。总之,SEVO适用于鸽子的麻醉。

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