Severe destructive sinusitis and orbital apex syndrome as a complication of intranasal cocaine abuse.

摘要

Intranasal cocaine abuse may cause significant local ischemia of sinonasal and midfacial bones and soft tissues, and result in nasal septal perforation or necrosis, osteocartilaginous necrosis, hard palate perforation, and pharyngeal wall ulcerations [1,2]. There are only a few reports that deal with the possible orbital and periocular complications [3-5]. We report a very uncommon case of long-standing intranasal cocaine abuse leading to severe paranasal sinus destruction, extending to the orbit and resulting in orbital apex syndrome.