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Shape-based ultrasound tomography using a Born model with application to high intensity focused ultrasound therapy

机译:基于Born模型的基于形状的超声层析成像技术在高强度聚焦超声治疗中的应用

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摘要

A shaped-based ultrasound tomography method is proposed to reconstruct ellipsoidal objects using a linearized scattering model. The method is motivated by the desire to detect the presence of lesions created by high intensity focused ultrasound (HIFU) in applications of cancer therapy. The computational size and limited view nature of the relevant three-dimensional inverse problem renders impractical the use of traditional pixel-based reconstruction methods. However, by employing a shape-based parametrization it is only necessary I to estimate a small number of unknowns describing the geometry of the lesion, in this paper assumed to be ellipsoidal. The details of the shape-based nonlinear inversion method are provided. Results obtained from a commercial ultrasound scanner and a tissue phantom containing a HIFU-like lesion demonstrate the feasibility of the approach where a 20 mm X 5 mm X 6 mm ellipsoidal inclusion was detected with an accuracy of around 5%. (c) 2008 Acoustical Society of America.
机译:提出了一种基于形状的超声层析成像方法,利用线性散射模型重建椭球体。该方法是出于在癌症治疗的应用中检测由高强度聚焦超声(HIFU)产生的病变的愿望的动机。相关三维逆问题的计算量和有限的视角性质使得使用传统的基于像素的重建方法变得不切实际。然而,通过采用基于形状的参数化,仅需估计少量描述病变几何形状的未知数即可,在本文中假设为椭圆形。提供了基于形状的非线性反演方法的详细信息。从商业超声扫描仪和包含HIFU样病变的组织体模获得的结果证明了该方法的可行性,该方法可检测到20 mm X 5 mm X 6 mm椭圆形包涵体,准确度约为5%。 (c)2008年美国声学学会。

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