Longterm Efficacy and Safety of Abatacept in Patients with Rheumatoid Arthritis Treated in Routine Clinical Practice: Effect of Concomitant Methotrexate after 24 Weeks

Takahashi Nobunori; Kojima Toshihisa; Kaneko Atsushi; Kida Daihei; Hirano Yuji; Fujibayashi Takayoshi; Yabe Yuichiro; Takagi Hideki; Oguchi Takeshi; Miyake Hiroyuki; Kato Takefumi; Watanabe Tsuyoshi; Hayashi Masatoshi; Kanayama Yasuhide; Funahashi Koji; Asai Shuji; Yoshioka Yutaka; Takemoto Toki; Terabe Kenya; Asai Nobuyuki; Ishiguro Naoki

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Longterm Efficacy and Safety of Abatacept in Patients with Rheumatoid Arthritis Treated in Routine Clinical Practice: Effect of Concomitant Methotrexate after 24 Weeks

机译：常规临床实践对类风湿关节炎患者的abatacept的长期疗效和安全性：24周后伴随甲氨蝶呤的影响

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Objective. Our study aimed to evaluate the longterm efficacy and safety of abatacept (ABA), and to explore factors that increase its longterm efficacy in patients with rheumatoid arthritis (RA) treated in routine clinical practice.

机译：目的。我们的研究旨在评估abatacept（ABA）的长期疗效和安全性，并探讨提高其在常规临床实践中治疗的类风湿关节炎（RA）患者中长期疗效的因素。

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《The Journal of rheumatology》 |2015年第5期|共8页
作者
Takahashi Nobunori; Kojima Toshihisa; Kaneko Atsushi; Kida Daihei; Hirano Yuji; Fujibayashi Takayoshi; Yabe Yuichiro; Takagi Hideki; Oguchi Takeshi; Miyake Hiroyuki; Kato Takefumi; Watanabe Tsuyoshi; Hayashi Masatoshi; Kanayama Yasuhide; Funahashi Koji; Asai Shuji; Yoshioka Yutaka; Takemoto Toki; Terabe Kenya; Asai Nobuyuki; Ishiguro Naoki;
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正文语种 eng
中图分类免疫性疾病;
关键词
RHEUMATOID ARTHRITIS; LONGTERM EFFECT; ABATACEPT; METHOTREXATE; MULTICENTER STUDIES;

机译：类风湿关节炎;长期效应;算术;甲氨蝶呤;多中心研究;

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1. Longterm Efficacy and Safety of Abatacept in Patients with Rheumatoid Arthritis Treated in Routine Clinical Practice: Effect of Concomitant Methotrexate after 24 Weeks [J] . Takahashi Nobunori, Kojima Toshihisa, Kaneko Atsushi, The Journal of rheumatology . 2015,第5期

机译：常规临床实践对类风湿关节炎患者的abatacept的长期疗效和安全性：24周后伴随甲氨蝶呤的影响
2. Efficacy and safety of abatacept for patients with Sjogren's syndrome associated with rheumatoid arthritis: Rheumatoid Arthritis with Orencia Trial toward Sjogren's syndrome Endocrinopathy (ROSE) trial an open-label, one-year, prospective study Interim analysis of 32 patients for 24 weeks [J] . Tsuboi Hiroto, Matsumoto Isao, Hagiwara Shinya, Modern rheumatology . 2015,第2期

机译：阿巴西普对类风湿性关节炎干燥综合征患者的疗效和安全性：类风湿性关节炎和Orencia试验用于干燥综合征的内分泌病（ROSE）试验为期一年，前瞻性开放性研究32位患者进行了为期24周的中期分析
3. Attainment and characteristics of clinical remission according to the new ACR-EULAR criteria in abatacept-treated patients with early rheumatoid arthritis: new analyses from the Abatacept study to Gauge Remission and joint damage progression in methotrexate (MTX)-naive patients with Early Erosive rheumatoid arthritis (AGREE) [J] . Josef S. Smolen, Jürgen Wollenhaupt, Juan J. Gomez-Reino, Arthritis Research . 2015,第1期

机译：根据新的ACR-EULAR标准，在接受abatacept治疗的早期类风湿性关节炎患者中达到和达到临床缓解的特征：从Abatacept研究到未接受甲氨蝶呤（MTX）的早期侵蚀性类风湿性关节炎患者的量表缓解和关节损伤进展的新分析（同意）
4. Immunogenic HLA-DR-presented-peptides Identified from Clinical Samples of Synovial Tissue/Fluid and Peripheral Blood from Patients with Rheumatoid Arthritis or Lyme Arthritis [C] . Qi Wang, Elise E. Drouin, Chunxiang Yao, ASMS Conference on Mass Spectrometry and Allied Topics . 2016

机译：免疫原性HLA-DR呈递肽，从类风湿性关节炎或莱姆关节炎患者的滑膜组织/液体和外周血的临床样本中鉴定出来
5. Clinical research on the preventive efficacy of sulfasalazine against Pneumocystis jirovecii pneumonia in patients with rheumatoid arthritis [D] . 布川貴博 2019

机译：柳氮磺胺吡啶对类风湿关节炎肺炎克氏杆菌的预防作用的临床研究
6. Efficacy and safety of abatacept for patients with Sjögrens syndrome associated with rheumatoid arthritis: Rheumatoid Arthritis with Orencia Trial toward Sjögrens syndrome Endocrinopathy (ROSE) trial—an open-label one-year prospective study—Interim analysis of 32 patients for 24 weeks [O] . Hiroto Tsuboi, Isao Matsumoto, Shinya Hagiwara, -1

机译：阿巴西普对类风湿性关节炎干燥综合征患者的疗效和安全性：类风湿性关节炎Orencia试验用于干燥综合征的内分泌病（ROSE）试验（一项开放性前瞻性前瞻性研究）对32例患者进行了为期24周的中期分析
7. Longterm safety, efficacy, and inhibition of structural damage progression over 5 years of treatment with abatacept in patients with rheumatoid arthritis in the abatacept in inadequate responders to methotrexate trial [O] . Kremer, Joel M, Peterfy, Charles, Russell, Anthony S, 2014

机译：在甲氨蝶呤试验不足的患者中，使用abatacept治疗风湿性关节炎患者中abatacept超过5年的长期安全性，疗效和对结构损伤进展的抑制作用

Longterm Efficacy and Safety of Abatacept in Patients with Rheumatoid Arthritis Treated in Routine Clinical Practice: Effect of Concomitant Methotrexate after 24 Weeks

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