An explanation of why the MGO level in manuka honey does not show the antibacterial activity

摘要

The following article by Professor Peter Molan is presented for your information. This debate is expected to continue through until this year s annual conference in Masterton. Following are some basic facts about methylgloxal: 1. Methylglyoxal is onechemical compound found in non-peroxide honey often branded and marketed as Unique Manuka Factor (UMF~(R)) 2. Methylglyoxal is one of a number of elements that make up the Unique Manuka Factor. 3. The research findings relating to methylgloxal was conducted in Germany, independent of New Zealand companies and in the public domain. 4. The measurement of the non-peroxide activity is a measure of an outcome (the action of the honey upon biological subject matter), while the measurement of methylglyoxal quantifies the presence of a chemical compound. 5. Methylglyoxal reacts differently to biological matter ('bugs') when in honey than on its own. 6. Other elements within the honey change how this chemical works.