Reflux of gastric juice and glue ear in children.

Tasker A; Dettmar PW; Panetti M; Koufman JA; Birchall JP; Pearson JP

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Reflux of gastric juice and glue ear in children.

机译：小儿胃液和耳胶反流。

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Otitis media with effusion (glue ear) is the most frequent cause of deafness in children. We investigated the role of gastric juice reflux in this disease. We measured pepsin concentrations in middle ear effusions from children using ELISA and enzyme activity assays. 45 (83%) of 54 effusions contained pepsin/pepsinogen at concentrations of up to 1000-fold greater than those in serum. Our data suggest that reflux of gastric juice could be a major cause of glue ear in children.

机译：中耳炎伴积液（胶耳）是儿童耳聋的最常见原因。我们调查了胃液反流在这种疾病中的作用。我们使用ELISA和酶活性测定法测量了儿童中耳积液中的胃蛋白酶浓度。 54种积液中有45种（83％）所含的胃蛋白酶/胃蛋白酶原的浓度比血清中高1000倍。我们的数据表明，胃液反流可能是儿童胶水耳朵的主要原因。

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来源
《The Lancet 》 |2002年第9305期| 共1页
作者
Tasker A; Dettmar PW; Panetti M; Koufman JA; Birchall JP; Pearson JP;
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正文语种 eng
中图分类医药、卫生 ;
关键词
Gastroesophageal Reflux; Otitis Media with Effusion; 胃食管反流; 中耳炎; 伴渗出液;

机译：Gastroesophageal Reflux;Otitis Media with Effusion;胃食管反流;中耳炎;伴渗出液;

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1. Reflux of gastric juice and glue ear in children. [J] . Tasker A, Dettmar PW, Panetti M, The Lancet . 2002 ,第9305期

机译：小儿胃液和耳胶反流。
2. Investigation of gastric pepsinogen in middle ear fluid of children with glue ear. [J] . Toros SZ, Toros AB, Ozel L, Acta Oto-Laryngologica . 2010 ,第11期

机译：胶耳朵儿童中耳液中胃蛋白酶原的调查。
3. Pepsin assay: a marker for reflux in pediatric glue ear. [J] . Abd-El-Fattah AM, Abdul-Maksoud GA, Ramadan AS, Otolaryngology--head and neck surgery: official journal of American Academy of Otolaryngology-Head and Neck Surgery . 2007 ,第3期

机译：胃蛋白酶测定：儿科胶耳返流的标志物。
4. Diagnosis of gastric cancer by peptidomic analysis of gastric juice [C] . Wei-Chao Chang, Ping-I Hsu, Yuan-Yan Chen, ASMS Conference on Mass Spectrometry and Allied Topics . 2008

机译：胃汁肽分析胃癌诊断
5. Kinetics of Gastric Juice Diffusion to Solid Food During Digestion. [D] . Widjaja, Jessica Maria. 2010

机译：消化过程中胃液向固体食物扩散的动力学。
6. Mixed reflux of gastric and duodenal juices is more harmful to the esophagus than gastric juice alone. The need for surgical therapy re-emphasized. [O] . W K Kauer, J H Peters, T R DeMeester, 1995

机译：胃液和十二指肠液的混合回流比单独的胃液对食道的危害更大。再次强调了对手术治疗的需要。
7. New insights in gastroesophageal reflux, esophageal function and gastric emptying in relation to dysphagia before and after anti-reflux surgery in children. [O] . Smits MJ, Loots CM, Benninga M A, 2013

机译：儿童反流手术前后吞咽困难与胃食管反流，食管功能和胃排空的新见解。
8. Otitis Media with Effusion in Young Children. Clinical Practice Guideline Number12; Managing Otitis Media with Effusion in Young Children. Quick Reference Guide for Clinicians Number 12; Middle Ear Fluid in Young Children: Consumer Version. Clinical Pract [R] . 1994

机译：中耳炎患儿的中耳炎。临床实践指南第12号;青少年积液治疗中耳炎。第12号临床医生快速参考指南;幼儿中耳液：消费者版。临床实践

Reflux of gastric juice and glue ear in children.

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