Effects of exogenous glucose on survival and infectivity of Schistosoma mansoni cercariae

摘要

The effects of exogenous glucose in artificial spring water (ASW) were studied on the survival and infeclivity of Schistosoma mansoni cercariae. The mean percent survival of cercariae maintained in 1 percent glucose in ASW for 36 and 48hr was significantly greater than that of cereariae maintained identically in ASW. Cercariae maintained in ASW with or without glucose for 24hr. fixed in neutral buffered formalin, and stained in Oil Red O, showed an accumulation of neutral lipid in the tail. Cercariae maintained as described above and stained in periodic acid-Schiff exhibited depleted glycogen. mainly from the tail. Cercariae maintained in ASW with glucose for 24hr did not resynlhesize glycogen, Cercariae maintained in ASW with glucose for 24hr were as capable of infecting male FVBN202 mice as were freshly emerged eereariae, and increased the percent of worm recovery. Exogeneous glucose added to ASW prolonged the survival of S. mansoni cercariae and increased infectivily in terms of worm recovery.