Copper(I)-Catalyzed Aryl Bromides To Form Intermolecular and Intramolecular Carbon—Oxygen Bonds

摘要

A highly efficient Cu-catalyzed C—O bond-forming reaction of alcohol and aryl bromides has been developed. This transformation was realized through the use of copper(I) iodide as a catalyst, 8-hydroxyquinoline as a ligand, and K_3PO_4 as a base. A variety of functionalized substrates were found to react under these reaction conditions to provide products in good to excellent yields.