Expedient and Rapid Synthesis of 1,2,3-Triazolo[5,1-c]morpholines through Palladium—Copper Catalysis

Chinmay Chowdhury; Sanjukta Mukherjee; Bimolendu Das; Basudeb Achari

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Expedient and Rapid Synthesis of 1,2,3-Triazolo[5,1-c]morpholines through Palladium—Copper Catalysis

机译：钯-铜催化快速合成1,2,3-三唑并[5,1-c]吗啉

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A one-pot approach using palladium—copper as catalyst hasbeen developed for the synthesis of morpholines fused with 1,2,3-triazole. Good regioselectivity, mild reaction conditions,high yields and short reaction time are the hallmarks of thismethod.

机译：已经开发出使用钯-铜作为催化剂的一锅法，用于合成与1,2,3-三唑稠合的吗啉。该方法具有良好的区域选择性，温和的反应条件，高收率和较短的反应时间。

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《The Journal of Organic Chemistry》 |2009年第9期|共4页
作者
Chinmay Chowdhury; Sanjukta Mukherjee; Bimolendu Das; Basudeb Achari;
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正文语种 eng
中图分类有机化学;
关键词
approach; morpholines; hallmarks;

机译：方法;吗啉;标志;

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1. Expedient and Rapid Synthesis of 1,2,3-Triazolo[5,1-c]morpholines through Palladium—Copper Catalysis [J] . Chinmay Chowdhury, Sanjukta Mukherjee, Bimolendu Das, The Journal of Organic Chemistry . 2009,第9期

机译：钯-铜催化快速合成1,2,3-三唑并[5,1-c]吗啉
2. Fused mesoionic heterocycles: synthesis of [1,2,3]triazolo[1,5-a]quinoline, [1,2,3]triazolo[1,5-a]quinazoline, [1,2,3]triazolo[1,5-a]quinoxaline and [1,2,3]triazolo[5,1-c]benzotriazine derivatives [J] . Abbott PA., Bonnert RV., Caffrey MV., Tetrahedron . 2002,第16期

机译：熔融中离子杂环：[1,2,3]三唑并[1,5-a]喹啉，[1,2,3]三唑并[1,5-a]喹唑啉，[1,2,3]三唑并[1]的合成，5-a]喹喔啉和[1,2,3]三唑并[5,1-c]苯并三嗪衍生物
3. An expedient and facile route for the general synthesis of 3-aryl substituted 1,2,3-triazolo[1,5-a][1,4]benzodiazepin-6-ones and 1,2,3-triazolo[1,5-a] [1,5]benzodiazocin-7-ones [J] . Chinmay Chowdhury, rnAnup Kumar Sasmal, rnBasudeb Achari Organic & biomolecular chemistry . 2010,第21期

机译：一般合成3-芳基取代的1,2,3-三唑并[1,5-a] [1,4]苯并二氮杂-1-酮和1,2,3-三唑并[1,5]的简便方法-a] [1,5]苯并二唑-7-酮
4. SYNTHESIS OF 3-5-METHYL-1-(4-METHYLPHENYL)-1,2,3-TRIAZOL-4-YL-6-SUBSTITUTED-s-TRIAZOLO3,4-b- 1,3,4THIADIAZOLES [C] . Heng-Shan Dong International symposium for Chinese organic chemists . 2000

机译：合成3- 5-甲基-1-（4-甲基苯基）-1,2,3-三唑-4-基 -6取代-S-TRIAZOLO 3,4-B - 1,3,4,3,4,3,4,3,4-二唑
5. Application of organocatalysis to the synthesis of chiral morpholines, piperazines, aziridines, azetidines, beta-fluoroamines, and gamma-fluoroamines; discovery of selective phospholipase D inhibitors with optimized in vivo properties. [D] . O'Reilly, Matthew C. 2014

机译：有机催化在合成手性吗啉，哌嗪，氮丙啶，氮杂环丁烷，β-氟胺和γ-氟胺中的应用；发现具有优化体内特性的选择性磷脂酶D抑制剂。
6. Asymmetric synthesis of chiral β-alkynyl carbonyl and sulfonyl derivatives via sequential palladium and copper catalysis [O] . Barry M. Trost, James T. Masters, Benjamin R. Taft, 2016

机译：连续钯和铜催化不对称合成手性β-炔基羰基和磺酰基衍生物
7. Synthesis of [1,2,3]triazolo[1,5-a][1,2,4]triazolo[5,1-c]pyrazines [O] . Tomaz Trcek, Bojan Vercek 2004

机译：[1,2,3]三唑并[1,5-a] [1,2,4]三唑并[5,1-c]吡嗪的合成

Expedient and Rapid Synthesis of 1,2,3-Triazolo[5,1-c]morpholines through Palladium—Copper Catalysis

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