Stereocontrolled synthesis of trans-cyclopropyl sulfones from terminal epoxides

摘要

(Figure presented) Treatment of a range of (enantiopure) epoxides with the sodium salt of diethyl (phenylsulfonyl)methylphosphonate in DME at 140 °C for 4 h gives a variety of (enantiopure) trans-cyclopropyl sulfones with high diastereoselectivity.