NbCl_3-Catalyzed intermolecular [2+2+2] Cycloaddition of alkynes and α,ω-dienes: Highly chemo- and regioselective formation of 5-ω-alkenyl-1,4-substituted-1,3-cyclohexadiene derivatives

摘要

Intermolecular [2+2+2] cycloaddition of tert-butylacetylene with α,ω-dienes was successfully achieved by NbCl_3(DME) catalyst to afford 5-ω-alkenyl-1,4-disubstituted-1,3-cyclohexadienes in excellent yields with high chemo- and regioselectivity.