Multi-walled carbon nanotubes as matrix solid-phase dispersion extraction adsorbent for simultaneous analysis of residues of nine organophosphorus pesticides in fruit and vegetables by rapid resolution LC-MS-MS

摘要

A method for simultaneous analysis of residues of nine organophosphorus pesticides in fruit and vegetables has been developed. It involves matrix solid-phase dispersion (MSPD) for preconcentration before rapid resolution liquid chromatography-tandem mass spectrometry (RRLC-MS-MS). In the MSPD pre-concentration step, the adsorptive performance of multi-walled carbon nanotubes (MWCNT) as MSPD adsorbent and elution with four solvents were investigated; in the LC separation step, a rapid resolution high-throughout LC column was used with gradient elution. The results of the research showed that the linear correlation coefficients (r ~2) of the method for the nine target analytes varied between 0.9942 and 0.9996, mean recovery was in the range 71.2-102.8%, with relative standard deviations (RSD) 2.0-11.8%, and limits of detection were all below 0.2 μg kg_(-1). The method was used for simultaneous analysis of the nine pesticides in eight different fruit and vegetable samples.