HPLC Resolution of the Enantiomers of Glycidyl Sulfides and Glycidyl Selenides on Amylose Tris-(Phenylcarbamate) Stationary Phase

摘要

The resolution of the enantiomers of a series of glycidyl sulfides and glycidyl selenides has been examined on a chiral stationary phase prepared by coating aminopropylated silica gel with amylose tris-(phenyl-carbamate). Most of the enantiomers of glycidyl monosulfides and monoselenides could be resolved satisfactorily but those of the disulfides could not. The effects of solute structure and of the concentration of 2-propanol in the mobile phase on retention and resolution were investigated.