NEW POLYBROMINATED DIPHENYL ETHER FROM THE MARINE SPONGE Dysidea herbaeea

摘要

Tropical marine sponges of the family Dysideidae contain a series of antimicrobial polybrominated diphenyl ethers with varying degrees of hydroxylation,methoxylation,and bromination [1].Recently this class of metabolites has attracted attention because of their ability to inhibit 15-lipoxygenase in mammals [2]and the assembly of microtubular proteins [3]and to regulate interleukin-8 production [4].