STEROIDAL COMPOUNDS FROM Helleborus caucasicus LEAVES

摘要

Interest in the genus Helleborus has heightened recently because it is a known source of cardiac glycosides of the bufadienolide group. Several new steroidal glycosides, ecdysteroids, representatives of a new class of natural compounds thionines, macrocyclic suboxides, etc. have been isolated from various Helleborus species in addition to bufadienolides. Total preparations of Helleborus have been used in medicine as analgesic, antirheumatic, and other agents. Mainly the subterrean organs of the plant are studied and used. The leaves have been neglected.