Report of the 10th annual international pachyonychia congenita consortium meeting

摘要

The International Pachyonychia Conge-nita Consortium (IPCC) was founded in 2004 in Park City, Utah, USA. The IPCC is a group of scientists and physicians who have agreed to work together to develop treatments and a cure for pachyonychia congenita, a rare kerati-nizing disorder (PC, OMIM #16700 and #167210). From February 14th to 17th, 2013, the group convened in Park City for their 10th annual meeting. The IPCC holds yearly meetings devoted to the most pressing issues in developing treatments for PC and strives to reach consensus on the best way to move forward. The 2013 meeting focused on how to best move forward with clinical trials and on learning from work in other scientific areas, with an emphasis on understanding mechanisms of pain and hyperkeratosis. Considerable time was spent on discussing the best way to move forward with the development of new treatments and how to obtain or develop tools that can measure treatment outcomes in PC.