A NOVEL INDOLOMONOTERPENIC ALKALOID FROM PROCESSED Strychnos nux-vomica

摘要

A novel indolomonoterpenic alkaloid, 4-hydroxy-19-methyl-16,19-seco-12,24-seco-strychnidine-10,16-dione (1), together with three known compounds 2–4 (vomicine, strychnine, and brucine), have been isolated from processed Strychnos nux-vomica. Its structure was determined by detailed spectral analysis (1H NMR,13C NMR, 1H–1H COSY, HMBC, and HR-ESI-MS).