Improved treatment for primary HIV infection by interferon-alfa therapy? Does HCV treatment in HIV/HCV coinfected patients help us to test this hypothesis?

摘要

To The Editor-With great interest we read the recent study by Azzoni et al [1] and the accompanying editorial by Mc-Namara and Collins [2]. The observed antiviral effects of interferon-a on human immunodeficiency virus (HIV) load have also been well documented in the large PEG-Interferon HIV/HCV Coin-fection registration trials. Here, a drop of HIV RNA of nearly 1 log was seen in HIV viremic patients treated with pegy-lated (Peg)-interferon for hepatitis C virus (HCV) infection alone [3].